Development of Experimental Genetic Tools for Campylobacter fetus

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Pathogenesis of Campylobacter fetus Infections

We developed a mouse model to compare the virulence of Campylobacter fetus strains with (S-plus) and without (Sminus) surface array protein (S-protein) capsules. In adult HA/ICR mice pretreated with ferric chloride, the LDF0 for S-plus strain 84-32 was 43.3 times lower than its spontaneous S-minus mutant 84-54. Seven strains of inbred mice were no more susceptible than the outbred strain. In co...

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Campylobacter Fetus Meningitis in Adults

The zoonotic pathogen Campylobacter fetus is a rare cause of bacterial meningitis. Little is known about the clinical characteristics, predisposing factors and outcome of C fetus meningitis in adults. We report cases of C fetus meningitis in a nationwide cohort study of adult bacterial meningitis patients in the Netherlands and performed a review of the literature. Two patients with C fetus men...

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Hippurate hydrolysis by Campylobacter fetus.

An additional method for differentiating between Campylobacter fetus subsp. jejuni and C. fetus subsp. intestinalis is reported. Strains of C. fetus subsp. jejuni (18/20) were shown to hydrolyze hippurate in the 2-h rapid test, whereas strains of C. fetus subsp. intestinalis did not.

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Improved media for growth and aerotolerance of Campylobacter fetus.

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 2007

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.02407-06